HIV PrEP Comparison
Truvada vs Descovy
Price comparison in Canada
Truvada starts at $40.00 per month, while Descovy starts at $845.00 per month in Canada. Truvada contains emtricitabine/tenofovir disoproxil, while Descovy contains emtricitabine/tenofovir alafenamide. Last updated: 2026-02-26.
Head-to-Head Comparison
| Truvada | Descovy | |
|---|---|---|
| Price Range | $40–$73 per month | $845–$1063 per month |
| Cheapest Pharmacy | Costco ($39.49 per month) | Costco ($844.49 per month) |
| Generic Name | emtricitabine/tenofovir disoproxil | emtricitabine/tenofovir alafenamide |
| Route | Oral tablet | Oral tablet |
| Category | HIV PrEP | HIV PrEP |
| ODB Coverage | General Benefit | Limited Use |
Pharmacy Total Breakdown
| Pharmacy | Truvada | Descovy |
|---|---|---|
| Costco | $39.49 per month | $844.49 per month |
| Walmart | $57.97 per month | $959.97 per month |
| Rexall | $66.99 per month | $1012.99 per month |
| Shoppers Drug Mart | $72.99 per month | $1062.99 per month |
Full Drug Pages
Frequently Asked Questions
- Which is cheaper, Truvada or Descovy?
- Truvada is generally cheaper, starting at $40.00 per month compared to $845.00 per month for Descovy. The lowest price is at Costco ($39.49 per month).
- What is the difference between Truvada and Descovy?
- Truvada (emtricitabine/tenofovir disoproxil) and Descovy (emtricitabine/tenofovir alafenamide) are different medications in the hiv prep category.
- Is Truvada or Descovy covered by provincial drug plans?
- Truvada: General Benefit on the Ontario Drug Benefit formulary. Descovy: Limited Use on the Ontario Drug Benefit formulary.
Last updated: 2026-02-26