Which is cheaper, Truvada or Descovy?

Truvada is generally cheaper, starting at $40.00/mo compared to $850.00/mo for Descovy. The lowest price is at Costco ($35.00/mo).

Is Truvada or Descovy covered by provincial drug plans?

Truvada: General Benefit on the Ontario Drug Benefit formulary. Descovy: Limited Use on the Ontario Drug Benefit formulary.

Truvada vs Descovy: Price Comparison in Canada (2026)

Name: Truvada vs Descovy: Price Comparison in Canada (2026)
Creator: TeleTest
Published: 2026-02-26

Truvada starts at $40/mo, while Descovy starts at $850/mo in Canada. Truvada contains emtricitabine/tenofovir disoproxil, while Descovy contains emtricitabine/tenofovir alafenamide. Last updated: 2026-02-26.

Head-to-Head Comparison

	Truvada	Descovy
Price Range	$40–$65/mo	$850–$1100/mo
Cheapest Pharmacy	Costco ($35.00/mo)	Costco ($840.00/mo)
Generic Name	emtricitabine/tenofovir disoproxil	emtricitabine/tenofovir alafenamide
Route	Oral tablet	Oral tablet
Category	HIV PrEP	HIV PrEP
ODB Coverage	General Benefit	Limited Use

Pharmacy Price Breakdown

Pharmacy	Truvada	Descovy
Costco	$35.00/mo	$840.00/mo
Walmart	$48.00/mo	$950.00/mo
Rexall	$54.00/mo	$1000.00/mo
Shoppers Drug Mart	$60.00/mo	$1050.00/mo

Full Drug Pages

Truvada emtricitabine/tenofovir disoproxil $40–$65/mo Descovy emtricitabine/tenofovir alafenamide $850–$1100/mo

Frequently Asked Questions

Which is cheaper, Truvada or Descovy?: Truvada is generally cheaper, starting at $40.00/mo compared to $850.00/mo for Descovy. The lowest price is at Costco ($35.00/mo).
What is the difference between Truvada and Descovy?: Truvada (emtricitabine/tenofovir disoproxil) and Descovy (emtricitabine/tenofovir alafenamide) are different medications in the hiv prep category.
Is Truvada or Descovy covered by provincial drug plans?: Truvada: General Benefit on the Ontario Drug Benefit formulary. Descovy: Limited Use on the Ontario Drug Benefit formulary.

Last updated: 2026-02-26