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Protopic starts at $65.00 per tube, while Elidel starts at $65.00 per tube in Canada. Protopic contains tacrolimus 0.1%, while Elidel contains pimecrolimus. Last updated: 2026-02-26.

Head-to-Head Comparison

Protopic Elidel
Price Range $65–$103 per tube $65–$105 per tube
Cheapest Pharmacy Costco ($64.49 per tube) Costco ($64.49 per tube)
Generic Name tacrolimus 0.1% pimecrolimus
Route Topical ointment Topical cream
Category Dermatology Dermatology

Pharmacy Total Breakdown

Pharmacy Protopic Elidel
Costco $64.49 per tube $64.49 per tube
Walmart $84.97 per tube $84.97 per tube
Rexall $94.99 per tube $97.99 per tube
Shoppers Drug Mart $102.99 per tube $104.99 per tube

Frequently Asked Questions

Which is cheaper, Protopic or Elidel?
Protopic is generally cheaper, starting at $65.00 per tube compared to $65.00 per tube for Elidel. The lowest price is at Costco ($64.49 per tube).
What is the difference between Protopic and Elidel?
Protopic (tacrolimus 0.1%) and Elidel (pimecrolimus) are different medications in the dermatology category. Protopic is a topical ointment, while Elidel is a topical cream.

Last updated: 2026-02-26

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