Which is cheaper, Eucrisa or Protopic?

Protopic is generally cheaper, starting at $65.00 per tube compared to $245.00 per tube for Eucrisa. The lowest price is at Costco ($64.49 per tube).

What is the difference between Eucrisa and Protopic?

Eucrisa (crisaborole) and Protopic (tacrolimus 0.1%) are different medications in the dermatology category.

Eucrisa vs Protopic: Price Comparison in Canada (2026)

Name: Eucrisa vs Protopic: Price Comparison in Canada (2026)
Creator: TeleTest
Published: 2026-02-26

Protopic starts at $65.00 per tube, while Eucrisa starts at $245.00 per tube in Canada. Eucrisa contains crisaborole, while Protopic contains tacrolimus 0.1%. Last updated: 2026-02-26.

Head-to-Head Comparison

	Eucrisa	Protopic
Price Range	$245–$373 per tube	$65–$103 per tube
Cheapest Pharmacy	Costco ($244.49 per tube)	Costco ($64.49 per tube)
Generic Name	crisaborole	tacrolimus 0.1%
Route	Topical ointment	Topical ointment
Category	Dermatology	Dermatology

Pharmacy Total Breakdown

Pharmacy	Eucrisa	Protopic
Costco	$244.49 per tube	$64.49 per tube
Walmart	$309.97 per tube	$84.97 per tube
Rexall	$342.99 per tube	$94.99 per tube
Shoppers Drug Mart	$372.99 per tube	$102.99 per tube

Full Drug Pages

Eucrisa crisaborole $245–$373 per tube Protopic tacrolimus 0.1% $65–$103 per tube

Frequently Asked Questions

Which is cheaper, Eucrisa or Protopic?: Protopic is generally cheaper, starting at $65.00 per tube compared to $245.00 per tube for Eucrisa. The lowest price is at Costco ($64.49 per tube).
What is the difference between Eucrisa and Protopic?: Eucrisa (crisaborole) and Protopic (tacrolimus 0.1%) are different medications in the dermatology category.

Last updated: 2026-02-26