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Zepbound starts at $158.00 per month, while Wegovy starts at $431.12 per month in Canada. Wegovy contains semaglutide, while Zepbound contains tirzepatide. Last updated: 2026-06-16.

Head-to-Head Comparison

Wegovy Zepbound
Price Range $431.12–$492.8 per month $158–$649.13 per month
Cheapest Pharmacy Costco ($431.12 per month) N/A
Generic Name semaglutide tirzepatide
Route Weekly injection Weekly injection
Category Weight Loss Weight Loss
ODB Coverage Not Covered Not Covered
Coverage Notes Not covered Not covered

Frequently Asked Questions

Which is cheaper, Wegovy or Zepbound?
Zepbound is generally cheaper, starting at $158.00 per month compared to $431.12 per month for Wegovy.
What is the difference between Wegovy and Zepbound?
Wegovy (semaglutide) and Zepbound (tirzepatide) are different medications in the weight loss category.
Is Wegovy or Zepbound covered by provincial drug plans?
Wegovy: Not Covered on the Ontario Drug Benefit formulary. Zepbound: Not Covered on the Ontario Drug Benefit formulary.

Last updated: 2026-06-16

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