Smoking Cessation Comparison
Varenicline vs Zyban
Price comparison in Canada
Zyban starts at $23.00 per month, while Varenicline starts at $43.00 per month in Canada. Varenicline contains varenicline (Champix), while Zyban contains bupropion 150mg. Last updated: 2026-02-26.
Head-to-Head Comparison
| Varenicline | Zyban | |
|---|---|---|
| Price Range | $43–$78 per month | $23–$47 per month |
| Cheapest Pharmacy | Costco ($42.49 per month) | Costco ($22.49 per month) |
| Generic Name | varenicline (Champix) | bupropion 150mg |
| Route | Oral tablet | Oral tablet |
| Category | Smoking Cessation | Smoking Cessation |
| ODB Coverage | General Benefit | General Benefit |
Pharmacy Total Breakdown
| Pharmacy | Varenicline | Zyban |
|---|---|---|
| Costco | $42.49 per month | $22.49 per month |
| Walmart | $61.97 per month | $35.97 per month |
| Rexall | $70.99 per month | $42.99 per month |
| Shoppers Drug Mart | $77.99 per month | $46.99 per month |
Full Drug Pages
Frequently Asked Questions
- Which is cheaper, Varenicline or Zyban?
- Zyban is generally cheaper, starting at $23.00 per month compared to $43.00 per month for Varenicline. The lowest price is at Costco ($22.49 per month).
- What is the difference between Varenicline and Zyban?
- Varenicline (varenicline (Champix)) and Zyban (bupropion 150mg) are different medications in the smoking cessation category.
- Is Varenicline or Zyban covered by provincial drug plans?
- Varenicline: General Benefit on the Ontario Drug Benefit formulary. Zyban: General Benefit on the Ontario Drug Benefit formulary.
Last updated: 2026-02-26