Skip to main content
Compare

Acyclovir starts at $12.00 per month, while Valacyclovir starts at $20.00 per month in Canada. Valacyclovir contains valacyclovir 500–1000mg, while Acyclovir contains acyclovir. Last updated: 2026-02-26.

Head-to-Head Comparison

Valacyclovir Acyclovir
Price Range $20–$40 per month $12–$30 per month
Cheapest Pharmacy Costco ($19.29 per month) Costco ($11.99 per month)
Generic Name valacyclovir 500–1000mg acyclovir
Route Oral tablet Oral/topical
Category Antiviral Antiviral
ODB Coverage General Benefit General Benefit

Pharmacy Total Breakdown

Pharmacy Valacyclovir Acyclovir
Costco $19.29 per month $11.99 per month
Walmart $30.37 per month $22.47 per month
Rexall $36.59 per month $27.99 per month
Shoppers Drug Mart $39.19 per month $29.99 per month

Frequently Asked Questions

Which is cheaper, Valacyclovir or Acyclovir?
Acyclovir is generally cheaper, starting at $12.00 per month compared to $20.00 per month for Valacyclovir. The lowest price is at Costco ($11.99 per month).
What is the difference between Valacyclovir and Acyclovir?
Valacyclovir (valacyclovir 500–1000mg) and Acyclovir (acyclovir) are different medications in the antiviral category. Valacyclovir is an oral tablet, while Acyclovir is an oral/topical.
Is Valacyclovir or Acyclovir covered by provincial drug plans?
Valacyclovir: General Benefit on the Ontario Drug Benefit formulary. Acyclovir: General Benefit on the Ontario Drug Benefit formulary.

Last updated: 2026-02-26

Get a prescription