Dermatology Comparison
Tretinoin vs Trifarotene
Price comparison in Canada
Tretinoin starts at $18/mo, while Trifarotene starts at $70/mo in Canada. Tretinoin contains tretinoin 0.025–0.1%, while Trifarotene contains trifarotene (Aklief). Last updated: 2026-02-26.
Head-to-Head Comparison
| Tretinoin | Trifarotene | |
|---|---|---|
| Price Range | $18–$35/mo | $70–$110/mo |
| Cheapest Pharmacy | Costco ($15.00/mo) | Costco ($65.00/mo) |
| Generic Name | tretinoin 0.025–0.1% | trifarotene (Aklief) |
| Route | Topical cream/gel | Topical cream |
| Category | Dermatology | Dermatology |
| ODB Coverage | General Benefit | Not listed |
Pharmacy Price Breakdown
| Pharmacy | Tretinoin | Trifarotene |
|---|---|---|
| Costco | $15.00/mo | $65.00/mo |
| Walmart | $22.00/mo | $82.00/mo |
| Rexall | $26.00/mo | $92.00/mo |
| Shoppers Drug Mart | $30.00/mo | $102.00/mo |
Full Drug Pages
Frequently Asked Questions
- Which is cheaper, Tretinoin or Trifarotene?
- Tretinoin is generally cheaper, starting at $18.00/mo compared to $70.00/mo for Trifarotene. The lowest price is at Costco ($15.00/mo).
- What is the difference between Tretinoin and Trifarotene?
- Tretinoin (tretinoin 0.025–0.1%) and Trifarotene (trifarotene (Aklief)) are different medications in the dermatology category. Tretinoin is a topical cream/gel, while Trifarotene is a topical cream.
- Is Tretinoin or Trifarotene covered by provincial drug plans?
- Tretinoin: General Benefit on the Ontario Drug Benefit formulary.
Last updated: 2026-02-26