Mental Health Comparison
Sertraline vs Duloxetine
Price comparison in Canada
Sertraline starts at $10.00 per month, while Duloxetine starts at $13.00 per month in Canada. Sertraline contains sertraline (Zoloft), while Duloxetine contains duloxetine (Cymbalta). Last updated: 2026-02-26.
Head-to-Head Comparison
| Sertraline | Duloxetine | |
|---|---|---|
| Price Range | $10–$28 per month | $13–$33 per month |
| Cheapest Pharmacy | Costco ($9.49 per month) | Costco ($12.49 per month) |
| Generic Name | sertraline (Zoloft) | duloxetine (Cymbalta) |
| Route | Oral tablet | Oral tablet |
| Category | Mental Health | Mental Health |
| ODB Coverage | General Benefit | General Benefit |
Pharmacy Total Breakdown
| Pharmacy | Sertraline | Duloxetine |
|---|---|---|
| Costco | $9.49 per month | $12.49 per month |
| Walmart | $19.97 per month | $23.97 per month |
| Rexall | $25.49 per month | $29.99 per month |
| Shoppers Drug Mart | $27.49 per month | $32.49 per month |
Full Drug Pages
Frequently Asked Questions
- Which is cheaper, Sertraline or Duloxetine?
- Sertraline is generally cheaper, starting at $10.00 per month compared to $13.00 per month for Duloxetine. The lowest price is at Costco ($9.49 per month).
- What is the difference between Sertraline and Duloxetine?
- Sertraline (sertraline (Zoloft)) and Duloxetine (duloxetine (Cymbalta)) are different medications in the mental health category.
- Is Sertraline or Duloxetine covered by provincial drug plans?
- Sertraline: General Benefit on the Ontario Drug Benefit formulary. Duloxetine: General Benefit on the Ontario Drug Benefit formulary.
Last updated: 2026-02-26