Weight Loss Comparison
Ozempic vs Zepbound
Price comparison in Canada
Generic semaglutide starts at $88.88 per month, while Zepbound starts at $319.00 per month in Canada. Ozempic contains semaglutide, while Zepbound contains tirzepatide. Last updated: 2026-07-22.
Head-to-Head Comparison
| Ozempic | Zepbound | |
|---|---|---|
| Lowest Available Price Range | Generic: $88.88–$103.53 per month | $319–$649.13 per month |
| Cheapest Pharmacy | Generic at Costco ($88.88 per month) | N/A |
| Generic Name | semaglutide | tirzepatide |
| Route | Weekly injection | Weekly injection |
| Category | Weight Loss | Weight Loss |
| ODB Coverage | Limited Use | Not Covered |
| Coverage Notes | Limited Use (Type 2 Diabetes only in ON) | Not covered |
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Frequently Asked Questions
- Which is cheaper, Ozempic or Zepbound?
- Generic semaglutide is generally cheaper, starting at $88.88 per month compared to $319.00 per month for Zepbound. The lowest price is at Costco ($88.88 per month).
- What is the difference between Ozempic and Zepbound?
- Ozempic (semaglutide) and Zepbound (tirzepatide) are different medications in the weight loss category.
- Is Ozempic or Zepbound covered by provincial drug plans?
- Ozempic: Limited Use on the Ontario Drug Benefit formulary. Zepbound: Not Covered on the Ontario Drug Benefit formulary.
Last updated: 2026-07-22