Weight Loss Comparison
Ozempic vs Zepbound
Price comparison in Canada
Zepbound starts at $158.00 per month, while Ozempic starts at $258.19 per month in Canada. Ozempic contains semaglutide, while Zepbound contains tirzepatide. Last updated: 2026-06-16.
Head-to-Head Comparison
| Ozempic | Zepbound | |
|---|---|---|
| Price Range | $258.19–$282 per month | $158–$649.13 per month |
| Cheapest Pharmacy | Costco ($258.19 per month) | N/A |
| Generic Name | semaglutide | tirzepatide |
| Route | Weekly injection | Weekly injection |
| Category | Weight Loss | Weight Loss |
| ODB Coverage | Limited Use | Not Covered |
| Coverage Notes | Limited Use (Type 2 Diabetes only in ON) | Not covered |
Full Drug Pages
Frequently Asked Questions
- Which is cheaper, Ozempic or Zepbound?
- Zepbound is generally cheaper, starting at $158.00 per month compared to $258.19 per month for Ozempic.
- What is the difference between Ozempic and Zepbound?
- Ozempic (semaglutide) and Zepbound (tirzepatide) are different medications in the weight loss category.
- Is Ozempic or Zepbound covered by provincial drug plans?
- Ozempic: Limited Use on the Ontario Drug Benefit formulary. Zepbound: Not Covered on the Ontario Drug Benefit formulary.
Last updated: 2026-06-16