Which is cheaper, Ozempic or Zepbound?

Ozempic is generally cheaper, starting at $258.00 per month compared to $435.00 per month for Zepbound. The lowest price is at Costco ($257.47 per month).

What is the difference between Ozempic and Zepbound?

Ozempic (semaglutide) and Zepbound (tirzepatide) are different medications in the weight loss category.

Is Ozempic or Zepbound covered by provincial drug plans?

Ozempic: Limited Use on the Ontario Drug Benefit formulary. Zepbound: Not Covered on the Ontario Drug Benefit formulary.

Ozempic vs Zepbound: Price Comparison in Canada (2026)

Name: Ozempic vs Zepbound: Price Comparison in Canada (2026)
Creator: TeleTest
Published: 2026-02-26

Ozempic starts at $258.00 per month, while Zepbound starts at $435.00 per month in Canada. Ozempic contains semaglutide, while Zepbound contains tirzepatide. Last updated: 2026-02-26.

Head-to-Head Comparison

	Ozempic	Zepbound
Price Range	$258–$291 per month	$435–$502 per month
Cheapest Pharmacy	Costco ($257.47 per month)	N/A
Generic Name	semaglutide	tirzepatide
Route	Weekly injection	Weekly injection
Category	Weight Loss	Weight Loss
ODB Coverage	Limited Use	Not Covered
Coverage Notes	Limited Use (Type 2 Diabetes only in ON)	Not covered

Full Drug Pages

Ozempic semaglutide $258–$291 per month Zepbound tirzepatide $435–$502 per month

Frequently Asked Questions

Which is cheaper, Ozempic or Zepbound?: Ozempic is generally cheaper, starting at $258.00 per month compared to $435.00 per month for Zepbound. The lowest price is at Costco ($257.47 per month).
What is the difference between Ozempic and Zepbound?: Ozempic (semaglutide) and Zepbound (tirzepatide) are different medications in the weight loss category.
Is Ozempic or Zepbound covered by provincial drug plans?: Ozempic: Limited Use on the Ontario Drug Benefit formulary. Zepbound: Not Covered on the Ontario Drug Benefit formulary.

Last updated: 2026-02-26