Which is cheaper, Ozempic or Zepbound?

Ozempic is generally cheaper, starting at $253.00/mo compared to $435.00/mo for Zepbound. The lowest price is at Costco ($252.98/mo).

What is the difference between Ozempic and Zepbound?

Ozempic (semaglutide) and Zepbound (tirzepatide) are different medications in the weight loss category.

Is Ozempic or Zepbound covered by provincial drug plans?

Ozempic: Limited Use on the Ontario Drug Benefit formulary. Zepbound: Not Covered on the Ontario Drug Benefit formulary.

Ozempic vs Zepbound: Price Comparison in Canada (2026)

Name: Ozempic vs Zepbound: Price Comparison in Canada (2026)
Creator: TeleTest
Published: 2026-02-26

Ozempic starts at $253/mo, while Zepbound starts at $435/mo in Canada. Ozempic contains semaglutide, while Zepbound contains tirzepatide. Last updated: 2026-02-26.

Head-to-Head Comparison

	Ozempic	Zepbound
Price Range	$253–$308/mo	$435–$502/mo
Cheapest Pharmacy	Costco ($252.98/mo)	N/A
Generic Name	semaglutide	tirzepatide
Route	Weekly injection	Weekly injection
Category	Weight Loss	Weight Loss
ODB Coverage	Limited Use	Not Covered
Coverage Notes	Limited Use (Type 2 Diabetes only in ON)	Not covered

Full Drug Pages

Ozempic semaglutide $253–$308/mo Zepbound tirzepatide $435–$502/mo

Frequently Asked Questions

Which is cheaper, Ozempic or Zepbound?: Ozempic is generally cheaper, starting at $253.00/mo compared to $435.00/mo for Zepbound. The lowest price is at Costco ($252.98/mo).
What is the difference between Ozempic and Zepbound?: Ozempic (semaglutide) and Zepbound (tirzepatide) are different medications in the weight loss category.
Is Ozempic or Zepbound covered by provincial drug plans?: Ozempic: Limited Use on the Ontario Drug Benefit formulary. Zepbound: Not Covered on the Ontario Drug Benefit formulary.

Last updated: 2026-02-26