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Ozempic starts at $258.00 per month, while Mounjaro starts at $301.00 per month in Canada. Ozempic contains semaglutide, while Mounjaro contains tirzepatide. Last updated: 2026-02-26.

Head-to-Head Comparison

Ozempic Mounjaro
Price Range $258–$291 per month $301–$502 per month
Cheapest Pharmacy Costco ($257.47 per month) N/A
Generic Name semaglutide tirzepatide
Route Weekly injection Weekly injection
Category Weight Loss Weight Loss
ODB Coverage Limited Use Limited Use
Coverage Notes Limited Use (Type 2 Diabetes only in ON) Not covered for weight loss

Frequently Asked Questions

Which is cheaper, Ozempic or Mounjaro?
Ozempic is generally cheaper, starting at $258.00 per month compared to $301.00 per month for Mounjaro. The lowest price is at Costco ($257.47 per month).
What is the difference between Ozempic and Mounjaro?
Ozempic (semaglutide) and Mounjaro (tirzepatide) are different medications in the weight loss category.
Is Ozempic or Mounjaro covered by provincial drug plans?
Ozempic: Limited Use on the Ontario Drug Benefit formulary. Mounjaro: Limited Use on the Ontario Drug Benefit formulary.

Last updated: 2026-02-26

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