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Metoprolol starts at $6/mo, while Bisoprolol starts at $8/mo in Canada. Metoprolol contains metoprolol tartrate (Lopressor), while Bisoprolol contains bisoprolol (Zebeta). Last updated: 2026-02-26.

Head-to-Head Comparison

Metoprolol Bisoprolol
Price Range $6–$18/mo $8–$20/mo
Cheapest Pharmacy Costco ($4.00/mo) Costco ($5.00/mo)
Generic Name metoprolol tartrate (Lopressor) bisoprolol (Zebeta)
Route Oral tablet Oral tablet
Category Cardiovascular Cardiovascular
ODB Coverage General Benefit General Benefit

Pharmacy Price Breakdown

Pharmacy Metoprolol Bisoprolol
Costco $4.00/mo $5.00/mo
Walmart $8.50/mo $10.00/mo
Rexall $10.80/mo $12.50/mo
Shoppers Drug Mart $12.50/mo $14.50/mo

Frequently Asked Questions

Which is cheaper, Metoprolol or Bisoprolol?
Metoprolol is generally cheaper, starting at $6.00/mo compared to $8.00/mo for Bisoprolol. The lowest price is at Costco ($4.00/mo).
What is the difference between Metoprolol and Bisoprolol?
Metoprolol (metoprolol tartrate (Lopressor)) and Bisoprolol (bisoprolol (Zebeta)) are different medications in the cardiovascular category.
Is Metoprolol or Bisoprolol covered by provincial drug plans?
Metoprolol: General Benefit on the Ontario Drug Benefit formulary. Bisoprolol: General Benefit on the Ontario Drug Benefit formulary.

Last updated: 2026-02-26

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