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Flonase starts at $20.00 per bottle, while Nasonex starts at $29.00 per bottle in Canada. Flonase contains fluticasone nasal, while Nasonex contains mometasone nasal. Last updated: 2026-02-26.

Head-to-Head Comparison

Flonase Nasonex
Price Range $20–$41 per bottle $29–$53 per bottle
Cheapest Pharmacy Costco ($19.49 per bottle) Costco ($28.49 per bottle)
Generic Name fluticasone nasal mometasone nasal
Route Nasal spray Nasal spray
Category Allergy Allergy
ODB Coverage General Benefit General Benefit

Pharmacy Total Breakdown

Pharmacy Flonase Nasonex
Costco $19.49 per bottle $28.49 per bottle
Walmart $31.97 per bottle $41.97 per bottle
Rexall $38.99 per bottle $48.99 per bottle
Shoppers Drug Mart $40.99 per bottle $52.99 per bottle

Frequently Asked Questions

Which is cheaper, Flonase or Nasonex?
Flonase is generally cheaper, starting at $20.00 per bottle compared to $29.00 per bottle for Nasonex. The lowest price is at Costco ($19.49 per bottle).
What is the difference between Flonase and Nasonex?
Flonase (fluticasone nasal) and Nasonex (mometasone nasal) are different medications in the allergy category.
Is Flonase or Nasonex covered by provincial drug plans?
Flonase: General Benefit on the Ontario Drug Benefit formulary. Nasonex: General Benefit on the Ontario Drug Benefit formulary.

Last updated: 2026-02-26

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