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Escitalopram starts at $10/mo, while Duloxetine starts at $12/mo in Canada. Escitalopram contains escitalopram (Cipralex, Lexapro), while Duloxetine contains duloxetine (Cymbalta). Last updated: 2026-02-26.

Head-to-Head Comparison

Escitalopram Duloxetine
Price Range $10–$22/mo $12–$25/mo
Cheapest Pharmacy Costco ($6.50/mo) Costco ($8.00/mo)
Generic Name escitalopram (Cipralex, Lexapro) duloxetine (Cymbalta)
Route Oral tablet Oral tablet
Category Mental Health Mental Health
ODB Coverage General Benefit General Benefit

Pharmacy Price Breakdown

Pharmacy Escitalopram Duloxetine
Costco $6.50/mo $8.00/mo
Walmart $11.50/mo $14.00/mo
Rexall $14.00/mo $17.00/mo
Shoppers Drug Mart $16.00/mo $19.50/mo

Frequently Asked Questions

Which is cheaper, Escitalopram or Duloxetine?
Escitalopram is generally cheaper, starting at $10.00/mo compared to $12.00/mo for Duloxetine. The lowest price is at Costco ($6.50/mo).
What is the difference between Escitalopram and Duloxetine?
Escitalopram (escitalopram (Cipralex, Lexapro)) and Duloxetine (duloxetine (Cymbalta)) are different medications in the mental health category.
Is Escitalopram or Duloxetine covered by provincial drug plans?
Escitalopram: General Benefit on the Ontario Drug Benefit formulary. Duloxetine: General Benefit on the Ontario Drug Benefit formulary.

Last updated: 2026-02-26

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