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Effexor starts at $13.00 per month, while Desvenlafaxine starts at $16.00 per month in Canada. Effexor contains venlafaxine XR, while Desvenlafaxine contains desvenlafaxine (Pristiq). Last updated: 2026-02-26.

Head-to-Head Comparison

Effexor Desvenlafaxine
Price Range $13–$33 per month $16–$38 per month
Cheapest Pharmacy Costco ($12.49 per month) Costco ($15.49 per month)
Generic Name venlafaxine XR desvenlafaxine (Pristiq)
Route Oral capsule Oral tablet
Category Mental Health Mental Health
ODB Coverage General Benefit Limited Use

Pharmacy Total Breakdown

Pharmacy Effexor Desvenlafaxine
Costco $12.49 per month $15.49 per month
Walmart $23.97 per month $27.97 per month
Rexall $29.99 per month $34.99 per month
Shoppers Drug Mart $32.49 per month $37.99 per month

Frequently Asked Questions

Which is cheaper, Effexor or Desvenlafaxine?
Effexor is generally cheaper, starting at $13.00 per month compared to $16.00 per month for Desvenlafaxine. The lowest price is at Costco ($12.49 per month).
What is the difference between Effexor and Desvenlafaxine?
Effexor (venlafaxine XR) and Desvenlafaxine (desvenlafaxine (Pristiq)) are different medications in the mental health category. Effexor is an oral capsule, while Desvenlafaxine is an oral tablet.
Is Effexor or Desvenlafaxine covered by provincial drug plans?
Effexor: General Benefit on the Ontario Drug Benefit formulary. Desvenlafaxine: Limited Use on the Ontario Drug Benefit formulary.

Last updated: 2026-02-26