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Effexor starts at $12/mo, while Desvenlafaxine starts at $15/mo in Canada. Effexor contains venlafaxine XR, while Desvenlafaxine contains desvenlafaxine (Pristiq). Last updated: 2026-02-26.

Head-to-Head Comparison

Effexor Desvenlafaxine
Price Range $12–$25/mo $15–$30/mo
Cheapest Pharmacy Costco ($8.00/mo) Costco ($11.00/mo)
Generic Name venlafaxine XR desvenlafaxine (Pristiq)
Route Oral capsule Oral tablet
Category Mental Health Mental Health
ODB Coverage General Benefit Limited Use

Pharmacy Price Breakdown

Pharmacy Effexor Desvenlafaxine
Costco $8.00/mo $11.00/mo
Walmart $14.00/mo $18.00/mo
Rexall $17.00/mo $22.00/mo
Shoppers Drug Mart $19.50/mo $25.00/mo

Frequently Asked Questions

Which is cheaper, Effexor or Desvenlafaxine?
Effexor is generally cheaper, starting at $12.00/mo compared to $15.00/mo for Desvenlafaxine. The lowest price is at Costco ($8.00/mo).
What is the difference between Effexor and Desvenlafaxine?
Effexor (venlafaxine XR) and Desvenlafaxine (desvenlafaxine (Pristiq)) are different medications in the mental health category. Effexor is a oral capsule, while Desvenlafaxine is a oral tablet.
Is Effexor or Desvenlafaxine covered by provincial drug plans?
Effexor: General Benefit on the Ontario Drug Benefit formulary. Desvenlafaxine: Limited Use on the Ontario Drug Benefit formulary.

Last updated: 2026-02-26

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